March Madness Betting: Biggest Line Moves Opening Round 2025 NCAA Tournament

Get the Full StoryThe men s 2025 NCAA Tournament tips off Tuesday, March 18 with the First Four play-in games. Then the madness begins Thursday and Friday with 32 college basketball games. Opening betting odds and notable lines moves and adjustments by the top sportsbooks as sharper and pro bettors place their bets and take a position on teams.

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